Study on the Quality Standard of Jinbo Capsule / 中国药房
China Pharmacy
;
(12): 4245-4246,4247, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-605221
ABSTRACT
OBJECTIVE:
To provide reference for the establishment of quality standard for Jinbo capsule.METHODS:
TLC was conducted for the qualitative identification of Phellodendron chinense and Melia toosendan in preparation;HPLC was used for the content determination of berberine hydrochloride in preparation;the column was Diamonsil C18 with mobile phase of acetoni-trile-0.1% phosphoric acid (50∶50,V/V) at flow rate of 1 ml/min,detection wavelength was 265 nm,column temperature was 25 ℃ and volume injection was 10 μl.RESULTS:
TLC spots of P. chinense and M. toosendan in preparation were clear and well-separated. The linear range of berberine hydrochloride was 0.044-0.154 mg/ml(r=0.999 9);RSDs of precision,reproducibili-ty and stability tests were no more than 2.0%,recovery was 98.36%-102.15%(RSD=1.11%,n=9).CONCLUSIONS:
The meth-od is simple,accurate and reproducible,and can be used for the quality control of Jinbo capsule.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Pesquisa qualitativa
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2015
Tipo de documento:
Artigo
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