Thrombolytic Therapy in Deep Vein Thrombosis
Journal of the Korean Society for Vascular Surgery
;
: 291-296, 1999.
Artigo
em Coreano
| WPRIM
| ID: wpr-60530
ABSTRACT
PURPOSE:
This investigation was to evaluate the efficacy of catheter-directed thrombolysis with urokinase in treating symptomatic deep vein thrombosis (DVT).METHODS:
Eight patients with DVT underwent treatment for 8 affected limbs. The average urokinase dose was 487.5 million IU (range, 1.5 million to 6.5 million IU) infused over an average of 48 hour (range 24~72 hours).RESULTS:
Lysis was complete in 5 (63%), and partial in 2 (25%), not achieved in 1 (12%). One chronically occluded proximal iliac vein through popliteal vein antegradely and tibial vein through internal jugular vein retrogradely could not be crossed with a guide wire. Angioplasty (n=3) and stent placement (n=1) were applied in three limbs with underlying venous stenosis. One limb among three limb of initial complete lysis was detected thrombus at femoral vein but this patient was asymptomatic at 6 month later. There were no major complications or clinically detectable pulmonary emboli.CONCLUSION:
This initial experience suggests that catheter-directed thrombolysis with urokinase for treatment of symptomatic DVT is safe and effective.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Veia Poplítea
/
Trombose
/
Veias
/
Ativador de Plasminogênio Tipo Uroquinase
/
Stents
/
Terapia Trombolítica
/
Angioplastia
/
Constrição Patológica
/
Trombose Venosa
/
Extremidades
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society for Vascular Surgery
Ano de publicação:
1999
Tipo de documento:
Artigo
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