The function of entecavir to Mig in patients with chronic hepatitis / 国际检验医学杂志
International Journal of Laboratory Medicine
; (12): 2661-2662,2666, 2016.
Article
em Zh
| WPRIM
| ID: wpr-605611
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the function of entecavir to γ‐interferon induced monokine(Mig) for chronic hepatitis B pa‐tients .Methods The 40 cases of chronic hepatitis B patients were treated with entecavir tablet .The Mig level were detected by ELISA in 40 patients in the time before and after treatment of 12 weeks and 24 weeks ;HBsAg ,HBeAg level were analyzed by using electrochemiluminescence and HBV‐DNA was tested by using real‐time quantitative PCR (FQ‐PCR) .Results Mig and HBsAg , HBeAg ,HBV DNA levels were significantly lower than before treatment in the 40 patients(P< 0 .05) .Compared with those in the time of 12 weeks after treatment ,those indexes after treatment 24 weeks were significantly decreased(P< 0 .05) .Conclusion Ente‐cavir treatment can reduce the level of Mig ,HBsAg and HBeAg ,HBV DNA ,and help to control disease progression in chronic hep‐atitis B .
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1
Índice:
WPRIM
Idioma:
Zh
Revista:
International Journal of Laboratory Medicine
Ano de publicação:
2016
Tipo de documento:
Article