Clinical Observation of Citalopram in the Treatment of Depression after Lung Cancer Operation / 中国药房
China Pharmacy
;
(12): 2415-2416,2417, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-605719
ABSTRACT
OBJECTIVE:
To observe clinical efficacy and safety of citalopram in the treatment of depression patients after lung cancer operation.METHODS:
114 depression patients after lung cancer operation were selected and randomly divided into observa-tion group and control group (n=57). Control group was given routine treatment as nutrition support and electrolyte balance,but had no anti-depression drugs;observation group was given Citalopram tablet 20 mg orally,qd. Two groups were treated for 6 weeks. Clinical efficacy,HAMD and HAMA scores,each score and total score of SF-36 were observed before and after treatment. The occurrence of ADR was recorded.RESULTS:
The total effective rate of observation group was 87.72%,which was significant-ly higher than that that of control group(71.93%),with statistical significance(P0.05);HAMA score and HAMD score of 2 groups decreased significantly after treatment,the observation group was lower than the control group;each score and total score of SF-36 increased significantly,the observation group was higher than the control group,with statistical sig-nificance(P<0.05). No obvious ADR was found in 2 groups.CONCLUSIONS:
Citalopram is effective and safe for depression af-ter lung cancer operation,can improve mental state and quality of life.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacy
Ano de publicação:
2016
Tipo de documento:
Artigo
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