Expression Pattern of Immunoproteasome Subunits in Human Thymus
Immune Network
;
: 285-288, 2009.
Artigo
em Inglês
| WPRIM
| ID: wpr-60577
ABSTRACT
The expression pattern of immunoproteasomes in human thymus has not been analyzed but may have important consequences during thymic selection. Here we examined the expression patterns of immunoproteasome subunits in fetal and adult thymic tissues by immunohistochemistry and found that all three subunits are expressed in both cortical and medullary stromal cells. These data suggest that thymic selection in human can be affected by peptide repertoires generated by immunoproteasomes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Timo
/
Imuno-Histoquímica
/
Células Estromais
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Immune Network
Ano de publicação:
2009
Tipo de documento:
Artigo
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