Interventional effect of mindfulness-based stress reduction on perceived stress and sleep disturbance in cancer patients:a systematic review / 重庆医学

ABSTRACT

Objective To systematically the effect of mindfulness-based stress reduction(MBSR) on improving perceived stress and sleep disturbance in cancer patients.Methods The databases of PubMed(Medline),Cochrane,BIOSIS Previews,Web of Science,CBM,CNKI,VIP and Wanfang Data were retrieved by computer,moreover the related journals and included reference literatures were retrieved by manual searching for finding the randomized controlled trials(RCTs) on the application of MBSR in perceived stress and sleep disturbance of cancer patients.Two reviewers independently screened the literatures according to the inclusion and exclusion criteria,extracted the data,and assessed the quality of RCTs.The meta analysis was conducted by adopting the RevMan 5.3 software.Results Nine RCTs involving 974 patients were included.The meta analysis results indicated that the improvement of perceived stress and sleep disturbance after intervention had statistical difference between the MBSR group and control group[MD=-4.63,95％CI(-5.10,-4.17),P＜0.01,MD=-2.18,95％CI (-2.35,-2.01),P＜0.01],but the difference after 3-month intervention between the two groups was not statistically significant.Conclusion The present evidences show that the MBSR method can relieve the perceived stress and sleep disturbance in cancer patients during a short period,but long term effect still needs to carry out more researches to be verified.