Correlation of sole prenatal indication to fetal chromosomal karyotype abnormality / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12): 163-166, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-608734
ABSTRACT
Objective To analysis the clinical high risk factors for fetal chromosomal abnormalities.Methods Amniocentesis,chromosomal karyotype analysis and other related methods were performed on 4829 pregnant women,who presented sole indication of prenatal diagnosis such as advanced age,high risk factors and fetal ultrasound abnormalities,for analyzing the correlations of those women to the incidence of fetal chromosomal abnormalities.Results The detection rates of abnormal karyotype were 5.0% (57/1143),1.7% (40/2367) and 4.3% (57/1319) in the older women group (age>35),abnormal maternal serological screening group and abnormal fetal ultrasound finding group,respectively.The detection rats of karyotype abnormality were 6.9% (23/333) in women with fetal congenital heart diseases,8.5% (20/234) in those with abnormal amniotic fluid,1.1% (1/89) in those with fetal ventriculomegaly,1.1% (10/898) in those with fetal intracardiac hyperechogenicity,5.9% (2/34) in those with fetal choroid cyst and 5.6% (1/18) in those with fetal renal pelvis broadening.Conclusion The pregnant women with age>35,fetal sonographic structural anomalies or two or more soft marker abnormalities should be prenatally diagnosed and doing the genetic counseling combined with the family history.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Fatores de risco
Idioma:
Chinês
Revista:
Medical Journal of Chinese People's Liberation Army
Ano de publicação:
2017
Tipo de documento:
Artigo
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