TURBt combined with internal iliac artery embolization in treatment of elderly invasive bladder cancer patients with high risk / 中国内镜杂志

ABSTRACT

Objective To investigate the clinical effect of transurethral resection of bladder tumor (TURBt) combined with internal iliac artery embolization in treatment of elderly invasive bladder cancer patients with high risk.Method From February 2010 to May 2016, 26 cases by ultrasonography, CT and cystoscopy were diagnosed with muscle invasive bladder cancer but high-risk patients cannot tolerate radical cystectomy with transurethral resection of bladder tumor (TURBt) combined with internal iliac artery infusion chemotherapy and embolization treatment, TURBt could be used in chemotherapy before or after chemotherapy, specific depending on the size of the tumor and the patient may be.Result The operation and internal iliac artery embolization chemotherapy in 26 patients were successfully completed. Preoperative embolization in 16 cases, 18 cases of postoperative chemoembolization 1 times, 2 times in 9 cases, 3 times in 5 cases,. Among them, 7 cases relapsed again, TURBt, 2 cases of recurrence, third cases of TURBt, 3 cases of recurrence of preoperative embolization chemotherapy 1 times. Transurethral resection of the prostate (TURP) in 6 patients with benign prostatic hyperplasia (BPH) and transurethral resection of the prostate. No serious complications associated with surgery, no perioperative death. Postoperative pathological report was a muscle invasive transitional cell carcinoma. No bone marrow suppression, anemia, liver and renal function damage and other serious side effects were not occurred during the chemotherapy. After the operation, the patients were followed up from 3 months to 6 years, 2 cases died within 2 years, 4 cases died within 2 to 5 years, 18 cases were alive, 2 cases were lost to follow-up.Conclusion For patients at high risk for muscle invasive bladder cancer, TURBt combined with internal iliac artery embolization chemotherapy, minimally invasive, less pain, less complications, to avoid the high risk of radical cystectomy and caused by urinary diversion due to the decline in the quality of life, can delay the disease progression. Safety and efficacy.