Diffusion tensor imaging tractography in assessing damage of limbic system pathways of relapsing-remitting multiple sclerosis patients / 中国医学影像技术
Chinese Journal of Medical Imaging Technology
;
(12): 1176-1180, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-610707
ABSTRACT
Objective To assess the damage of limbic system pathways in relapsing-remitting multiple sclerosis (RRMS) by diffusion tensor imaging (DTI) tractography.Methods DTI tractography was used to acquire fiber numbers,fractional anisotropy (FA),mean diffusivity (MD) of cingulum,fornix,and uncinate fasciculus (UF) in 20 RRMS patients (MS group) and 20 healthy volunteers (control group),and statistical analysis was performed.Results Compared with control group,lower FA value (P<0.01) and higher MD value (P<0.05) were found in cingulum,fornix and UF of MS group,and the fiber numbers of fornix decreased in MS group (P<0.001).There were significant differences between the left and the right UF in fiber numbers and FA value of control group and the fiber numbers of MS group.Negative correlations were found between FA value of cingulum and UF and EDSS scores in MS group (r=-0.572,-0.665,both P<0.05),and positive correlations were found between MD value and EDSS scores (r=0.627,0.603,both P<0.05).Conclusion DTI tractography is valuable in assessing MS associated limbic system damage and in monitoring the clinical progression of the disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Medical Imaging Technology
Ano de publicação:
2017
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS