Antihypertensive effect of manidipine hydrochloride (Madiplot) in Hanoi Huu Nghi Hospital (2001-2002)

ABSTRACT

49 male patients between 45 and 70 years of age with hypertension and type 2 diabetes were studied to evaluate the effect of manidipine hydrochloride (Madiplot produced by Takeda - Japan) and side effects of this medication. Patients were taken 10-20 mg manidipine/day during 6 months. The result showed that manidipine reduced systolic blood pressure, diastolic blood pressure, and average blood pressure significantly but did not change heart rate during treatment period. Side effects were not much and this medication can be used to treat hypertension for long time