Research advances in clinicopathological features of patients with chronic HBV infection and normal alanine aminotransferase level / 临床肝胆病杂志

ABSTRACT

It was generally considered that patients with chronic HBV infection and normal alanine aminotransferase (ALT) level had no or mild liver pathological changes,but in recent years,a large number of studies have found that such patients may also have marked inflammation and fibrosis in the liver.This article discusses the association between clinical features and liver pathological features in patients with chronic HBV infection and normal ALT level and points out that age,sex,HBeAg status,HBV DNA load,ALT level,and liver stiffness measurement are associated with liver pathological changes.Monitoring of these clinical indices helps with early detection of liver pathological changes in patients with chronic HBV infection and normal ALT level.