Comparative study of simple curative effect of endoscopic sinus surgery and postoperative radiotherapy for esophageal cancer / 中国生化药物杂志

ABSTRACT

Objective To retrospectively analyze the clinical efficacy of simple endoscopic surgery and postoperative radiotherapy for esophageal cancer. Methods Kaplan-meier method and Cox regression model were used to analyze 101 cases of stage Ⅱa-Ⅲ esophageal cancer patients in 2011. Among them, 41 cases were treated with simple operation and 60 cases were treated with radiotherapy. The survival time and survival rate of the two groups were compared and analyzed Factors that affect their survival time. Results The median survival time was 31 months in the surgery group and 36 months in the radiotherapy group. The survival rate was 80%, 31%, 16% for 1, 3, and 5 years in the surgery alone group, 78%, 42% and 27% in the postoperative radiotherapy group, the overall survival rate was not statistically significant. The survival rate of patients with stage Ⅱb-Ⅲ was statistically significant (χ2= 4.02, P<0.05). Factors affecting the prognosis of esophageal squamous cell carcinoma and postoperative radiotherapy, tumor size, staging, smoking history. Conclusion There is no significant difference in the overall survival rate of esophageal squamous cell carcinoma between simple surgery and postoperative radiotherapy, but postoperative radiotherapy can improve the survival rate of patients with stage Ⅱb-Ⅲ.