Clinical analysis of nutritional support for patients with esophageal cancer after operation with fat emulsion amino acids (17) and glucose (11%) injection / 中国生化药物杂志

ABSTRACT

Objective To analyze the clinical effect of nutritional support for postoperative patients with esophageal cancer with fat emulsion and amino acids (17) and glucose (11%) injection (Calvin injection). Methods A total of 68 patients with esophageal cancer treated in the chest surgery in our hospital from December 2014 to December 2016 were selected and randomly divided into two groups with 34 cases in each group. All patients were treated with surgery for esophageal cancer. The patients in the study group were treated with Calvin injection after operation while patients in the control group were treated with conventional fluid replacement therapy. Subjective comprehensive assessment (SGA) was used to assess the nutritional status of the patients and the weight, serum total protein (TSP), serum albumin (Alb), transferrin (TF) content, urea nitrogen content in on one week, malnutrition improvement and complications of the patients in two groups were recorded and compared. Results The weight of the patients with esophageal cancer in the two groups after operation was decreased, and the weight loss of the patients in the study group was lower than that of the control group and the difference was statistically significant (P<0.01). The decrease degree of TSP, Alb and TF in the study group was lower than that in the control group, and the difference was statistically significant (P<0.05). The negative nitrogen balance of the two groups was improved, and the improvement of the negative nitrogen balance in the study group was better than that in the control group, and the difference was statistically significant (P<0.01). The postoperative malnutrition in the patients with esophageal cancer was improved. The improvement degree of malnutrition in the study group was better than that in the control group, and the difference was statistically significant (P<0.05). The incidence of complications in the study group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion Compared with the traditional method of postoperative fluid replacement, Calvin injection can improve the recovery of the body function of the patients with esophageal cancer after operation, improve the patient's negative nitrogen balance and nutritional status, reduce the incidence of complications, and improve the clinical prognosis. This treatment is safer and more effective and it is worth popularizing in clinical practice.