Hedgehog signaling pathway and cartilage damage / 中华地方病学杂志
Chinese Journal of Endemiology
;
(12): 621-624, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-613245
ABSTRACT
Hedgehog signaling pathway plays an key role in the process of endochondral bone formation, regulating the proliferation and differentiation of chondrocytes in epiphyseal growth plate. In recent years, it has been found that abnormal expression of Hedgehog signaling pathway-related molecules is involved in a variety of osteoarthropathy. Therefore, studying the relationship between Hedgehog signaling pathway and cartilage damage is of great significance to elucidate the molecular mechanism of osteoarthropathy. In this paper, we focus on the research progress of Hedgehog signaling pathway in chondrocyte proliferation, differentiation, apoptosis and cartilage matrix metabolism, which may provide new insights into mechanism and prevention of osteoarthropathy.
Texto completo:
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Endemiology
Ano de publicação:
2017
Tipo de documento:
Artigo
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