New discoveries about the role of SREBPs in the pathogenesis and targeted therapy of gynecological tumors / 中国综合临床

ABSTRACT

Objective Sterol regulatory element-binding proteins(SREBPs) are a family of nuclear transcription factors that regulate lipid metabolism in eukaryotic cells.They are over expressedin many malignant tumors,and closely related to tumor initiation and progression.We briefly summarize the research advancement of SREBPs in gynecological tumors.