Analysis of clinical curative effect of phentolamine combined with pituitrin in the treatment of senile bronchiectasis with massive hemoptysis / 中国基层医药

ABSTRACT

Objective To explore the clinical efficacy and safety of pituitrin and phentolamine in the treatment of senile bronchiectasis with massive hemoptysis,thus to provide guidance for the clinical.Methods 80 elderly patients were selected as the subjects of this experiment,and the patients were randomly divided into two groups using the envelope random grouping method.40 patients in the control group used phentolamine.40 cases in the observation group were treated with pituitrin and phentolamine.The clinical curative effect,bleeding time,bleeding volume and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 92.50％,which was significantly higher than 70.00％ of the control group (x2 =6.646,P ＜ 0.05).The bleeding time,total amount of bleeding of the observation group were significantly less than those of the control group (tbleeding time =5.069,tbleeding volurne =5.447,all P ＜ 0.05).The incidence rate of adverse reaction in the observation group was 7.50％,which was significantly lower than 27.50％ of the control group (x2 =5.541,P ＜ 0.05).Conclusion Phentolamine combined with pituitrin in the treatment of senile bronchiectasis with massive hemoptysis can significantly relieve symptoms,shorten the bleeding time,reduce the total amount of bleeding,reduce the probability of adverse reactions in patients.