Research progress of early enteral nutrition in acute pancreatitis / 肠外与肠内营养

ABSTRACT

Nowadays,acute pancreatitis remains a clinical challenge with considerable morbidity and mortality.Acute pancreatitis is associated with systemic and metabolic derangements which may promote hypermetabolism and negative nitrogen balance due to negative energy balance.Therefore,optimal nutritional support intreatmentof acute pancreatitis has been a subject for decades.Originally,the concept of pancreatic rest by fasting was thought to improve outcome as early enteral nutrition was believed to aggravate inflammation or infection through pancreatic stimulation.At present,an increasing number of studieswere performed showing numerousbenefits of enteral nutrition.In this review,intestinal dysfunctionandroute,timing,type and amount of enteralnutritional support in acute pancreatitis will be discussed.