Application of UTMD mediated microRNA transfection in disease treatment / 医学研究生学报

ABSTRACT

In recent years, research about microRNA has been increasing.How to safely and effectively introduce microRNA into target cells and target tissues is the key to successful treatment of diseases using microRNA.Many studies have reported that ultrasound-targeted microbubble destruction technology (UTMD) mediated gene transfection has the advantages of safety, targeting and high transfection efficiency.The research of UTMD mediated microRNA transfection has also increased year by year.The mechanism of UTMD mediated microRNA transfection and the application in the treatment of diseases such as cancer and cardiovascular system are reviewed in this paper.