Control of Food Intake by Gastrointestinal Peptides: Mechanisms of Action and Possible Modulation in the Treatment of Obesity
Journal of Neurogastroenterology and Motility
;
: 180-196, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-61978
ABSTRACT
This review focuses on the control of appetite by food intake-regulatory peptides secreted from the gastrointestinal tract, namely cholecystokinin, glucagon-like peptide 1, peptide YY, ghrelin, and the recently discovered nesfatin-1 via the gut-brain axis. Additionally, we describe the impact of external factors such as intake of different nutrients or stress on the secretion of gastrointestinal peptides. Finally, we highlight possible conservative—physical activity and pharmacotherapy—treatment strategies for obesity as well as surgical techniques such as deep brain stimulation and bariatric surgery also altering these peptidergic pathways.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peptídeos
/
Apetite
/
Colecistocinina
/
Peptídeo YY
/
Trato Gastrointestinal
/
Estimulação Encefálica Profunda
/
Ingestão de Alimentos
/
Peptídeo 1 Semelhante ao Glucagon
/
Cirurgia Bariátrica
/
Grelina
Idioma:
Inglês
Revista:
Journal of Neurogastroenterology and Motility
Ano de publicação:
2017
Tipo de documento:
Artigo
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