A Case of Mitochondrial Myopathy Showing Severe Hypoxemia during REM Sleep / 수면정신생리
Sleep Medicine and Psychophysiology
;
: 49-53, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-61992
ABSTRACT
Mitochondrial myopathy is characterized by variable clinical manifestations from mild limb weakness to fatal respiratory failure and central nervous system sequela. But it is a rare event that sleep disordered breathing become a clue of diagnosis for mitochondrial myopathy. We report a case of a 21 year-old man who was diagnosed as mitochondrial myopathy during the investigation for the possible cause of chronic hypoventilation syndrome. Before being admitted to our hospital, he was suspected as having sleep apnea syndrome in another hospital. We re-evaluated the history, physical examination, laboratoy findings and polysomnography in detail. Severe hypoxemia was noted during REM sleep on nocturnal polysomnography and the diagnosis of mitochondrial myopathy was made by muscle biopsy in rectus abdominis muscle. We treated him with bilevel positive airway pressure therapy during sleep and it could reverse the hypoxemia during REM sleep. He could be discharged with improved condition and is being well with the use of this ventilatory assistance.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Exame Físico
/
Insuficiência Respiratória
/
Síndromes da Apneia do Sono
/
Sono REM
/
Biópsia
/
Sistema Nervoso Central
/
Polissonografia
/
Miopatias Mitocondriais
/
Reto do Abdome
/
Diagnóstico
Tipo de estudo:
Estudo diagnóstico
Limite:
Humanos
Idioma:
Coreano
Revista:
Sleep Medicine and Psychophysiology
Ano de publicação:
2007
Tipo de documento:
Artigo
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