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Robotic-assisted laparoscopic prostatectomy in patients with high-risk prostate cancer :experiences of 400 cases / 中华泌尿外科杂志
Chinese Journal of Urology ; (12): 424-427, 2017.
Artigo em Chinês | WPRIM | ID: wpr-620217
ABSTRACT
Objective To study the short-term effectiveness of robotic-assisted laparoscopic radical prostatectomy in high-risk prostate cancer.Methods From March 2012 to March 2017,400 patients with high-risk prostate who underwent robotic-assisted laparoscopic radical prostatectomy were reviewed.The median age was 68 years old(ranged from 49 to 83 years),and the median PSA was 23.1 ng/ ml(ranged from 5.2 to 999.0 ng/ml).Preoperative parameters,surgical interventional data,postoperative pathology and follow-up data were collected.Logistic regression was used to analyze the risk factors of positive surgical margin in postoperative pathology.Results All the operations were successfully completed.Median operation time was 115 min(ranged 50-555 min),and median estimated blood loss was 110 ml(ranged 30-500 ml).Six patients had perioperative complications,among which two were rectal injury,two were cardio-cerebrovascular disease and two were hemorrhage.There was no perioperative death.Positive surgical margin was detected in 151 patients,accounting for 37.8%.A total of 345 cases (86.3%) underwent lymphadenectomy,of which 253 cases (63.3%) were performed standardized resection and 92 cases (23%) were performed extensive resection.The median number of resected lymph nodes was 9 (ranged 3-36).Eighty cases (23.2%,80/345) were positive in resected lymph nodes.Regression analysis showed that preoperative PSA > 20 ng / ml or clinical stage ≥ T2c were risk factors for positive surgical margins.After a median follow-up of 14.4 months (ranged 2.0-58.8 months),the overall incidence of biochemical recurrence was 33.4% (107/320),and the urinary continence rate one year after operation was 86.6% (277/320).Conclusions Robotic-assisted laparoscopic radical prostatectomy in patients with high-risk prostate cancer was a feasible,safe and effective approach.Preoperative PSA and clinical stage were the risk factors for positive surgical margin.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de etiologia / Fatores de risco Idioma: Chinês Revista: Chinese Journal of Urology Ano de publicação: 2017 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de etiologia / Fatores de risco Idioma: Chinês Revista: Chinese Journal of Urology Ano de publicação: 2017 Tipo de documento: Artigo