Effect of periopusside administration of ambroxol combined with psychological intervention on patients with lung cancer after thoracoscopic lobectomy / 中国生化药物杂志

ABSTRACT

Objective To investigate the effect of perindox administration combined with psychological intervention on patients with lung cancer after thoracoscopic lobectomy.Methods Fifty patients with lung cancer underwent thoracoscopic lobectomy from November 2015 to November 2016 in our hospital were randomly divided into experimental group and experimental group according to the time of hospitalization.Control group, 25 cases.The rats in the experimental group were treated with ambroxol hydrochloride(600 mg/d)from the day of operation to the postoperative 3d administration.The control group was treated with the same volume of saline.At the same time, the experimental group was treated with psychological intervention and the necessary psychological guidance was carried out.The data were collected and compared with the two groups before and after the general information, intraoperative conditions, lung function before and after surgery and blood gas analysis Results , mechanical ventilation time, early postoperative complications, postoperative hospital stay and treatment costs.ResultsThere were no cases of death in the perioperative period.Compared with the control group, the total incidence of postoperative complications was not significant, but the pulmonary complications were significantly reduced, only 1 case and 9 cases in the control group The In addition, the postoperative mechanical ventilation, ICU time, postoperative hospital stay, total treatment costs, the difference between the two groups was significant, the data were statistically significant(P<0.05).Conclusion The patients with lung cancer underwent thoracoscopic lobectomy with high dose intravenous ambroxol hydrochloride in the perioperative period can greatly improve the postoperative pulmonary function and reduce the postoperative complications, and effectively reduce the postoperative hospitalization Time, the material pressure on the patient is further reduced.