Amniotic fluid chromosome detection for 95 NIPT high-risk pregnant women / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 1749-1750,1753, 2017.
Artigo
em Chinês
| WPRIM
| ID: wpr-621075
ABSTRACT
Objective To analysis of the detection result of amniotic fluid chromosome which in NIPT high-risk pregnant women.Methods Amniotic fluid cells via amniotic cavity puncture were cultured and analyzed,the chromosome karyotypes were observed.Results The highest positive predictive value of NIPT was for trisomy 21(85.00%),then trisomy 18(75.00%),sex chromosome abnormalities(68.00%),other chromosome abnormalities(41.67%),trisomy 13 (25.00%).Conclusion The highest accuracy of NIPT was shown in detection of Down''s syndrome by NIPT.NIPT was screening test which is effective and noninvasive in prenatal diagnosis.Amniotic fluid Chromosomal karyotype analysis was the gold standard in the diagnosis of fetal chromosomal disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo prognóstico
Idioma:
Chinês
Revista:
International Journal of Laboratory Medicine
Ano de publicação:
2017
Tipo de documento:
Artigo
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