Serum TRACP5b detection and its significance in breast cancer with negative axillary lymph nodes / 中华内分泌外科杂志
Chinese Journal of Endocrine Surgery
; (6): 377-379, 2011.
Article
em Zh
| WPRIM
| ID: wpr-622143
Biblioteca responsável:
WPRO
ABSTRACT
Objective To study the value of serum tartrate-resistant acid phosphatase 5b (TRACP5b) in bone metastasis in early breast cancer patients with negative axillary lymph nodes.Methods The serum level of TRACP5b was determined by enzyme-linked immumosorbent assay (ELISA) in 26 breast cancer patients and 18 healthy female adults.Results The serum level of TRACP5b was (3.85 ± 0.85) U/L in the group of breast cancer patients and (2.08 ± 0.84) U/L in the control group.The difference had statistical significance (P <0.05 ).The sensitivity was 42.31% and the specificity was 94.44% for TRACP5 b in predicting bone metastasis of breast cancer with negtive axillary lymph nodes.Conclusions TRACP5b has higher sensitivity and specificity in breast cancer patients than in healthy female adults.TRACP5b is a useful serum marker to predict bone metastasis in breast cancer patients.
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Índice:
WPRIM
Tipo de estudo:
Diagnostic_studies
Idioma:
Zh
Revista:
Chinese Journal of Endocrine Surgery
Ano de publicação:
2011
Tipo de documento:
Article