Clozapine Re-Challenge With Lithium Supplementation Following Clozapine-Induced Neutropenia
ASEAN Journal of Psychiatry
;
: 90-92, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-626268
ABSTRACT
Objectives:
This paper aims to report on a case in which re-challenging with clozapine in combination with lithium in a patient who developed neutropenia was carried out.Methods:
The patient was treated with clozapine for treatmentresistant schizophrenia. After five weeks he showed much improvement but developed neutropenia. Withdrawal of clozapine brought on a relapse of psychotic symptoms. Subsequently, clozapine was reintroduced along with Lithium. The neutrophil count was monitored closely.Results:
The neutrophil and white blood cell count were noted to return to normal upon re-challenging, and the patient’s clinical condition also improved.Conclusion:
Simultaneous administration of lithium and clozapine to patients experiencing neutropenia on clozapine is a possible strategy. However, very close monitoring of the white count is needed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Esquizofrenia
/
Clozapina
/
Lítio
/
Neutropenia
Idioma:
Inglês
Revista:
ASEAN Journal of Psychiatry
Ano de publicação:
2014
Tipo de documento:
Artigo
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