Hospital outcomes of adult respiratory tract infections with extended-spectrum b-lactamase (ESBL) producing Klebsiella pneumonia
Malaysian Journal of Medical Sciences
;
: 36-40, 2007.
Artigo
em Malaiala
| WPRIM
| ID: wpr-627337
ABSTRACT
Klebsiella pneumoniae ranks high as a cause of adult pneumonia requiring hospitalization in Malaysia. To study whether extended-spectrum b-lactamase (ESBL) producing K. pneumoniae was linked to hospital outcomes, we retrospectively studied 441 cases of adult respiratory tract infections with microbial proven K. pneumoniae from an urban-based university teaching hospital between 2003 and 2004. 47 (10.6%) cases had ESBL. Requirement for ventilation and median length of hospital stay, were greater in ‘ESBL’ than in ‘non-ESBL’ group [34% vs. 7.4%, p<0.001; 14 days vs. 5 days, p<0.001 respectively] but not crude hospital mortality rate [21.3% vs. 12.4%, p=0.092]. There was a four-fold increased risk of requiring ventilation [4.61 (2.72-7.85)] when ESBL was present. Our findings support the association of ESBL producing K. pneumoniae with adversed hospital outcomes and reiterate the need for vigilance on the part of treating clinicians.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Hospitais
Limite:
Adulto
Idioma:
Malaiala
Revista:
Malaysian Journal of Medical Sciences
Ano de publicação:
2007
Tipo de documento:
Artigo
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