Associations of MRI-lesions and clinical features with disability in Chinese patients with multiple sclerosis
Neurology Asia
;
: 391-399, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-628568
ABSTRACT
Objective:
To analyze associations of MRI-lesions and clinical features with disability in patients with multiple sclerosis (MS) in Shanghai, China.Methods:
We studied patients with MS, identified from a survey in Shanghai, whose sites of lesions in the CNS was based on the MRI examinations. Associations between MRI-lesions, various clinical variables and the severity of disability were analyzed with univariate and multivariate logistic regression analysis.Results:
There were 210 patients in this study. The disability of the patients with lesions confined to the spinal cord was significantly more severe than those with lesions in the brain (p < 0.008). Current age (OR 1.041, 95% CI 1.007~1.077), MS duration (OR 1.082, 95% CI 1.011~1.159) and MRI-lesions in the spinal cord (OR 2.441, 95% CI 1.039~5.737) were significantly associated with severity of disability on multivariate logistic regression analysis.Conclusion:
MRI-lesions in the spinal cord, older age, a longer MS duration were significantly associated with a more severe disability in this MS study in Shanghai China.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Neurology Asia
Ano de publicação:
2013
Tipo de documento:
Artigo
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