Pantothenate kinase associated neurodegeneration (PKAN) presenting as a seizure disorder

ABSTRACT

Pantothenate kinase associated neurodegeneration (PKAN) is an uncommon degenerative disease of the basal ganglia caused by mutations in the PANK2 gene. We describe a 19-years-old man with clinically and radiologically diagnosed case of PKAN, who presented with generalized tonic clonic seizures 2 years preceding other classical extrapyramidal features of the disease. PKAN presenting with seizure has not, to our knowledge, been reported previously.