Target-controlled Infusion Propofol Versus Sevoflurane Anaesthesia for Emergency Traumatic Brain Surgery: Comparison of the Outcomes
Malaysian Journal of Medical Sciences
;
: 73-82, 2017.
Artigo
em Inglês
| WPRIM
| ID: wpr-629072
ABSTRACT
Background:
The choice of anaesthetic techniques is important for the outcome of traumatic brain injury (TBI) emergency surgery. The objective of this study was to compare patient outcomes for target-controlled infusion (TCI) of propofol and sevoflurane anaesthesia.Methods:
A total of 110 severe TBI patients, aged 18–60, who underwent emergency brain surgery were randomised into Group T (TCI) (n = 55) and Group S (sevoflurane) (n = 55). Anaesthesia was maintained in Group T with propofol target plasma concentration of 3–6 μg/mL and in Group S with minimum alveolar concentration (MAC) of sevoflurane 1.0–1.5. Both groups received TCI remifentanil 2–8 ng/mL for analgesia. After the surgery, patients were managed in the intensive care unit and were followed up until discharge for the outcome parameters.Results:
Demographic characteristics were comparable in both groups. Differences in Glasgow Outcome Scale (GOS) score at discharge were not significant between Group T and Group S (P = 0.25) the percentages of mortality (GOS 1) [27.3% versus 16.4%], vegetative and severe disability (GOS 2–3) [29.1% versus 41.8%] and good outcome (GOS 4–5) [43.6% versus 41.8%] were comparable in both groups. There were no significant differences in other outcome parameters.Conclusion:
TCI propofol and sevoflurane anaesthesia were comparable in the outcomes of TBI patients after emergency surgery.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Inglês
Revista:
Malaysian Journal of Medical Sciences
Ano de publicação:
2017
Tipo de documento:
Artigo
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