Sample Size Calculation in Animal Studies Using Resource Equation Approach
Malaysian Journal of Medical Sciences
; : 101-105, 2017.
Article
em En
| WPRIM
| ID: wpr-629075
Biblioteca responsável:
WPRO
ABSTRACT
Animal research plays an important role in the pre-clinical phase of clinical trials. In animal studies, the power analysis approach to sample size calculation is recommended. Whenever it is not possible to assume the standard deviation and the effect size, an alternative to the power analysis approach is the ‘resource equation’ approach, which sets the acceptable range of the error degrees of freedom (DF) in an analysis of variance (ANOVA). The aim of this article is to guide researchers in calculating the minimum and maximum numbers of animals required in animal research by reformulating the error DF formulas.
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Índice:
WPRIM
Idioma:
En
Revista:
Malaysian Journal of Medical Sciences
Ano de publicação:
2017
Tipo de documento:
Article