Interaction between insulin-like growth factor-1 with other growth factors in serum depleted culture medium for human cartilage engineering
The Medical Journal of Malaysia
;
: 7-8, 2004.
Artigo
em Malaiala
| WPRIM
| ID: wpr-629915
ABSTRACT
The regulation roles of insulin-like growth factor-1 (IGF-1) with basic fibroblast growth factor (bFGF) and transforming growth factor beta 2 (TGFbeta2) in human nasal septum chondrocytes monolayer culture and cartilage engineering was investigated in this study. The role of IGF-1 with bFGF and TGFbeta2 was investigated by measuring chondrocyte growth kinetic and collagen genes expression. IGF-1 together with bFGF and TGFbeta2 promote cartilage tissue engineering, increase type II collagen expression and enhance the histological features of engineered cartilage.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fator de Crescimento Insulin-Like I
/
Cartilagem
/
Expressão Gênica
/
Divisão Celular
/
Substâncias de Crescimento
/
Meios de Cultura Livres de Soro
/
Condrócitos
/
Colágeno Tipo II
/
Engenharia Tecidual
Idioma:
Malaiala
Revista:
The Medical Journal of Malaysia
Ano de publicação:
2004
Tipo de documento:
Artigo
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