In vitro development of autologous tissue engineered human articular neocartilage for orthopaedic surgery
The Medical Journal of Malaysia
;
: 15-16, 2004.
Artigo
em Malaiala
| WPRIM
| ID: wpr-629917
ABSTRACT
Treatment of articular cartilage lesions remains a clinical challenge. The uses of prosthetic joint replace allograft and/or autograft transplant carry a risk of complications due to infection, loosening of its component, immunological rejection and morbidity at the donor site. There has been an increasing interest in the management of cartilage damages, owing to the introduction of new therapeutic options. Tissue engineering as a method for tissue restoration begins to provide a potential alternative therapy for autologous grafts transplantations. We aimed to evaluate how well a tissue engineered neocartilage implant, consist of human articular chondrocytes cultured with the presence of autologous serum and mixed in a fresh fibrin derived from patient, would perform in subcutaneous implantation in athymic mice.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenômenos Biomecânicos
/
Cartilagem Articular
/
Condrócitos
/
Procedimentos Ortopédicos
/
Meios de Cultura
/
Engenharia Tecidual
/
Soro
/
Camundongos Nus
Idioma:
Malaiala
Revista:
The Medical Journal of Malaysia
Ano de publicação:
2004
Tipo de documento:
Artigo
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