The fundamentals of tissue engineering: new scaffolds
The Medical Journal of Malaysia
;
: 89-90, 2004.
Artigo
em Malaiala
| WPRIM
| ID: wpr-629937
ABSTRACT
The ability to regenerate new bone for skeletal use is a major clinical need. In this study, two novel porous calcium phosphate materials pure HA and biphasic HA/beta-Tricalcium phosphate (HA/beta -TCP) were evaluated as potential scaffolds for cell-seeded bone substitutes using human osteoblast-like cells (HOS) and primary human mesenchymal stem cells (hMSCs). A high rate of proliferation was observed on both scaffolds. A greater increase in alkaline phosphatase (ALP- an indicator of osteoblast differentiation) was observed on HA/beta -TCP compared to HA. This observation indicates that HA/TCP may play a role in inducing osteoblastic differentiation. Although further evaluation is required both materials show potential as innovative synthetic substitutes for tissue engineered scaffolds.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Técnicas de Cultura de Órgãos
/
Segurança
/
Queratinócitos
/
Imunoterapia Adotiva
/
Condrócitos
/
Engenharia Tecidual
/
Equipamentos e Provisões
/
Japão
País/Região como assunto:
Ásia
Idioma:
Malaiala
Revista:
The Medical Journal of Malaysia
Ano de publicação:
2004
Tipo de documento:
Artigo
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