Induced pluripotent stem cells in research and therapy
The Malaysian Journal of Pathology
;
: 1-13, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-630138
ABSTRACT
Induced pluripotent stem cells (iPSC) are derived from human somatic cells through ectopic expression of transcription factors. This landmark discovery has been considered as a major development towards patient-specifi c iPSC for various biomedical applications. Unlimited self renewal capacity, pluripotency and ease of accessibility to donor tissues contribute to the versatility of iPSC. The therapeutic potential of iPSC in regenerative medicine, cell-based therapy, disease modelling and drug discovery is indeed very promising. Continuous progress in iPSC technology provides clearer understanding of disease pathogenesis and ultimately new optimism in developing treatment or cure for human diseases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
The Malaysian Journal of Pathology
Ano de publicação:
2012
Tipo de documento:
Artigo
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