Risk factors for nosocomial infections in pediatric intensive care unit

ABSTRACT

A prospective cohort study was conducted on 671 patients, who were admitted to the pediatric intensive care unit of the Children Hospital N0 1 in the period of 14 months, to identify risk factors for nosocomial infections (NI). Results: NI rate was 22.9% and 29.3/1000 patient-days, in which nosocomial pneumonia accounted for 49.4%, surgical site infection 12.3%, catheter site infection 11.7%, urinary tract infection 5.8%. There is no significant difference of NI rate in age and sex (p>0.05). By multiple logistic regression analysis, the risk factors for NI were 2nd degree malnutrition, PRISM score, multiple invasive interventions, antibiotic therapy, H2 receptor blocker, parenteral nutrition. Risk factors for nosocomial pneumonia were intubation, duration of intubation >5 days, reintubation, H2 receptor blockers, aspiration. Risk factors for blood stream infection included venous cutdown, central venous catheter, duration of central venous catheter >3 days, parenteral nutrition. The risk factors for surgical site infection consisted of gastrointestinal surgery, post operative drain, duration of drain >5 days. The risk factors for urinary tract infection were urinary catheter, duration of urinary catheter >3 days