A Case of Angiosarcoma Arising from the Eyelid

ABSTRACT

PURPOSE: To report a case of angiosarcoma arising from the eyelid. CASE SUMMARY: A 72-year-old male patient presented with swelling and erythema on the upper and lower eyelid of 10 months in duration. After the diagnosis of cutaneous angiosarcoma via tissue biopsy, no evidence of systemic metastasis was found. The right eyelid was treated with radiation therapy and a partial clinical response was achieved. After 4 months of follow-up, swelling and a red-purple plaque developed on the same (right) eyelid. Another biopsy was performed and the histological examination indicated a recurrence of angiosarcoma. Neither local nor distant metastases were observed. However, large-sized and ill-defined margins warranted size reduction by paclitaxel neoadjuvant chemotherapy, followed by surgical excision and eyelid reconstruction. CONCLUSIONS: Angiosarcoma commonly occurs on the face and scalp, but rarely occurs on the eyelids. Herein, the authors report a case of angiosarcoma arising from the eyelid.