Significant Symptom Relief with Hepatic Artery Embolization in a VIPoma with Liver Metastases / 대한내과학회지
Korean Journal of Medicine
; : 363-368, 2014.
Article
em En
| WPRIM
| ID: wpr-63184
Biblioteca responsável:
WPRO
ABSTRACT
Vasoactive intestinal polypeptide-secreting tumors (VIPomas) cause VIPoma syndrome, which is characterized by watery diarrhea, hypokalemia, and achlorhydria. The treatment options for metastatic VIPomas include somatostatin analogs, cytoreductive surgery, and chemotherapy. We report the case of a 54-year-old male who presented with a peripancreatic mass with multiple hepatic metastases on computed tomography. After resection, the peripancreatic mass was demonstrated pathologically to be a neuroendocrine tumor. Although the patient received systemic chemotherapy and somatostatin analogs for the hepatic metastatic masses, the tumor increased in size. The patient then experienced severe diarrhea, despite treatment with the somatostatin analogs. Elevated serum VIP levels (3,260 pg/mL) and typical symptoms confirmed the diagnosis of VIPoma. We performed hepatic artery embolization (HAE) to reduce the tumor volume and control his symptoms, which led to a very rapid symptomatic response. The patient has remained symptom-free for 18 months with repeated HAE.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Acloridria
/
Somatostatina
/
Tumores Neuroendócrinos
/
Vipoma
/
Carga Tumoral
/
Diagnóstico
/
Diarreia
/
Tratamento Farmacológico
/
Artéria Hepática
/
Hipopotassemia
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
Idioma:
En
Revista:
Korean Journal of Medicine
Ano de publicação:
2014
Tipo de documento:
Article