Rosai-Dorfman disease presenting as recurrent nasal polyposis
Philippine Journal of Otolaryngology Head and Neck Surgery
;
: 22-24, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-632416
ABSTRACT
@#OBJECTIVES:
To present a case of Rosai-Dorfman disease in an individual with a 14-year history of recurrent nasal polyposis and discuss its clinical presentation, physical examination, radiologic findings, histopathologic characteristics and available treatment.METHODS:
Design:
Case ReportSetting:
Tertiary Government Hospital Patient OneRESULTS:
A 26-year-old Filipino diagnosed and repeatedly treated medically and surgically for recurrent nasal polyposis underwent repeat endoscopic sinus surgery. A histopathologic impression of Rosai-Dorfman disease was confirmed by positive S-100 and CD1a negative immunochemistry in conjunction with the morphologic findings.CONCLUSION:
Rosai-Dorfman disease is a rare entity which should be considered when dealing with recurrent nasal polyposis that is intractable to initial medical and surgical therapies. Histopathologic findings of emperipolesis and immunohistochemical S-100 stains play a key role in the diagnosis but there is yet no definite treatment for this disease.
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Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Histiocitose Sinusal
/
Emperipolese
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
Philippine Journal of Otolaryngology Head and Neck Surgery
Ano de publicação:
2014
Tipo de documento:
Artigo
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