Concise Review: Differentiation of Human Adult Stem Cells Into Hepatocyte-like Cells In vitro
International Journal of Stem Cells
;
: 49-54, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-63302
ABSTRACT
Adult stem cells (ASCs) are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues, which are the powerful sources for cell therapy and tissue engineering. Bone marrow-derived mesenchymal stem cells (BMSCs), adipose tissue-derived mesenchymal stem cells (ADSCs), and peripheral blood monocytes (PBMCs) are the common ASCs, and many studies indicated that ASCs isolated from various adult tissues could be induced to hepatocyte-like cells in vitro. However, the isolation, culture protocols, characterization of ASCs and hepatocyte-like cells are different. This review aims to describe the isolation and culture procedures for ASCs, to summarize the molecular characterization of ASCs, to characterize function of hepatocyte-like cells, and to discuss the future role of ASCs in cell therapy and tissue engineering.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Monócitos
/
Engenharia Tecidual
/
Células-Tronco Adultas
/
Células-Tronco Mesenquimais
/
Terapia Baseada em Transplante de Células e Tecidos
Tipo de estudo:
Guia de Prática Clínica
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
International Journal of Stem Cells
Ano de publicação:
2014
Tipo de documento:
Artigo
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