A 5 year retrospective review of pregnancy loss among women with polycystic ovarian morphology

ABSTRACT

BACKGROUND: Polycystic ovarian morphology is the most common ultrasound abnormality among women with recurrent pregnancy loss and as such, its presence has been postulated to have a relationship with a high rate of miscarriage among women conceiving spontaneously. Objective: The study aimed to determine the prevalence of pregnancy loss among women who have polycystic ovaries on ultrasound, at a tertiary hospital from January 2010 to December 2015.MATERIALS AND METHODS: A cross-sectional investigation involving a retrospective review of hospital records of 377 women who were diagnosed with polycystic ovaries on transvaginal ultrasound was performed. Their pregnancy outcomes were followed up by retrieving their medical charts at the outpatient department, consultants' clinics and the medical records section. Approval from the Independent Ethics Committee and Center for Clinical Epidemiology and Biostatistics was obtained.RESULTS: Of the 377 women with polycystic ovarian morphology, 280 (74.27%) met the 2003 Rotterdam criteria for polycystic ovary syndrome. The prevalence of pregnancy loss was 40.23%, while the live birth rate was 59.77% among the 377 women with polycystic ovaries on ultrasound. The majority of pregnancy loss occurred in the first trimester of pregnancy with a mean age of gestation of 8.9 ± 4.8 weeksCONCLUSION: The prevelance of pregnancy loss among women with polycystic ovarian morphology was 40.23%