Recurrent hydatidiform mole with NLRP7 mutation: The first confirmed case in the Philippines / Philippine Journal of Obstetrics and Gynecology
Philippine Journal of Obstetrics and Gynecology
; : 27-32, 2017.
Article
em En
| WPRIM
| ID: wpr-633540
Biblioteca responsável:
WPRO
ABSTRACT
High gravidity hydatidiform mole (HM) without normal pregnancy is very rare. The challenge of managing such cases will dwell on the concern of having normal conception versus having another molar gestation and its neoplastic sequelae. Presented in this paper is a case of a 32-year-old, gravida 5 para 0 (0040) who was admitted for the management of her fifth molar pregnancy. She underwent suction curettage and administration of methotrexate chemoprophylaxis. Genetic testing was done, which revealed a homozygous mutation in NLRP7, the gene implicated in recurrent molar gestations. This paper discusses the proper approach to determine the cause of recurrent molar pregnancies, as well as the management and prognosis of such cases.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Prognóstico
/
Curetagem a Vácuo
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Mola Hidatiforme
/
Testes Genéticos
/
Metotrexato
/
Quimioprevenção
/
Número de Gestações
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Homozigoto
/
Dente Molar
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Mutação
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Philippine Journal of Obstetrics and Gynecology
Ano de publicação:
2017
Tipo de documento:
Article