Advances in molecular genetic study on pathological myopia relevant gene loci / 中华实验眼科杂志

ABSTRACT

Pathological myopia(PM)is one of the global leading causes of blindness because of its severe optic complications.Previous researches implicated that hereditary factors play crucial roles in the pathogenesis of PM,and plenty molecular genetic studies,such as gene mapping and candidate gene screening,have been done to identify gene loci linked to PM.The newest advances in molecular genetic study on pathological myopia relevant gene loci were reviewed,including non-syndrome PM and system disease associated with PM.