Clinical Analysis of Virus-Associated Hemophagocytic Syndrome in Children / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
;
(24)1986.
Artigo
em Chinês
| WPRIM
| ID: wpr-638381
ABSTRACT
Objective To increase the awareness of virus-associated hemophagocytic syndrome.Methods Sixteen cases of virus-associated hemophagocytic syndrome were retrospectively analyzed.Results All presented with persistent high fever,cytopenia,hepato-splenomegaly,hepatic dysfunction,hypertriglyceridemia,hyperferritinemia,coagulopathy,hypofibrinogenemia,cytokine storm and a low natural killer cell activity.All patients had lymphohistiocytic accumulation in bone marrow.Treatment with high-dose gamma-globulin and high-dose methylprednisolone.Clinical symptoms and laboratory improved,and five patients died.Conclusion Aggressive early diagnosis and treatment are critical to improve survival.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo de rastreamento
Idioma:
Chinês
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
1986
Tipo de documento:
Artigo
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