Effect of Esomeprazole,Clarithromycin,Metronidazole Triple Therapy for Helicobactor Pylori Infection in Children / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2004.
Article
em Zh
| WPRIM
| ID: wpr-639155
Biblioteca responsável:
WPRO
ABSTRACT
Objective To study the effect of esomeprazole,clarithromycin,metronidazole triple therapy for helicobactor pylori(Hp) infection in children.Methods Ninty-eight cases of children,identified by ~ 13 C-urea breath test(~ 13 C-UBT) Hp infection,deparded into therapy group(66 cases) and control group(32 cases).Therapy group were given Esomeprazole[0.8 mg/(kg?d),1 time/d],clarithromycin[15 mg/(kg?d),2 times/d],metronidazole[30 mg/(kg?d),3 times/d]triple therapy.Control group were given the same treatment except ameprazole.The course was 1 week.They were followed up 4 weeks later after the course and re-tested by ~ 13 C-UBT.Results The recurrent abdominal pain of the two groups recovered in different degrees,and the efficacy rate was 100%.The eradication rate of Hp in therapy group and control group were separately 90.9%(60/66) and 87.5%(28/32).There was no significance difference of the eradication of Hp.Conclusions The trearment of esomeprazole,clarithromycin,metronidazole triple therapy on Hp infection in children is quite effective and safe.The side effect is moderate.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
2004
Tipo de documento:
Article