Cellular and Humoral Immunity in Children with Recurrent Respiratory Tract Infection / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2003.
Article
em Zh
| WPRIM
| ID: wpr-639237
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the cellular and humoral immunity in children with recurrent respiratory tract infection(RRI).Methods Fresh peripheral blood samples were treated and run through the flow cytometry,the percentage of lymphocytes subsets were acquired using Simultest software simulaneously. Immunoglobulin IgA,IgG,IgM and complement C3 and C4 were measured.Results The levels of IgG and IgA in the RRI group were lower than the normal reference value in only 1 patient respectively.The level of IgM decreased in 7cases.Complement C3 and C4 decreased in 3 and 1 patients, respectively.The percentage of CD8 in the RRI group was higher than that in healthy control group(P=0),and the CD4/CD8 was obviously lower than that in healthy control group(P=0.002).Conclusions The disorder of cellular and humoral immunity are existing and cell-mediated immune disorder is more obviously in RRI.The immune-modulation agents are necessary in the prevention and treatment for RRI.
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WPRIM
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
2003
Tipo de documento:
Article