Effect of photochemotherapy on expression of gelatases / 上海第二医科大学学报
Journal of Shanghai Jiaotong University(Medical Science)
;
(6)2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-641366
ABSTRACT
Objective To determine the effect of photochemotherapy on the expression of gelatinases. Methods Reverse transcription-polymerase chain reaction and gelatine zymography were employed to detect the effect of photochemotherapy on the expression and bioactivity of gelatinases at mRNA and protein levels respectively. Results Combination of ultraviolet A(UVA,0.8-2.0 J/cm2) and 8-methoxypsoralen(8-MOP,100 ng/mL) resulted in a decrease in the expression and bioactivity of gelatinases. Conclusion Photochemotherapy can inhibit the angiogenesis of endothelial cells through downregulating the expression and bioactivity of gelatinases.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Shanghai Jiaotong University(Medical Science)
Ano de publicação:
2006
Tipo de documento:
Artigo
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