Contrast Nephrotoxicity Associated with Emergency CT scans
Journal of the Korean Society of Emergency Medicine
;
: 157-161, 2003.
Artigo
em Coreano
| WPRIM
| ID: wpr-64212
ABSTRACT
PURPOSE:
In the last 30 years, there has been a markedly increased use of iodinated contrast agents in diagnostic and interventional radiological procedures. Due to the possible side effect of nephrotoxicity of these radiocontrast agents, we investigated the incidence of nephrotoxicity and attempted to identify the patient groups at higher risk for contrast nephrotoxicity among the patients who underwent emergency computerized tomography.METHODS:
We reviewed the medical records of 1,572 patients who had undergone contrast computerized tomography at the Emergency Center, Yonsei Medical Center, from January to May 2002. We defined contrast nephrotoxicity as any increase in the creatinine value of more than 0.5 mg/dL (44 micromol/L) or 25% compared to the baseline value.RESULTS:
We found 21 patients (1.3%) who met the criterion for contrast nephrotoxicity 13 patients with normal renal function, and 8 patients with a higher than normal creatinine value before contrast-enhanced computerized tomography. The incidence of contrast nephrotoxicity in the patient group with normal renal function was 0.8% (13/1551), compared to 38.1% (8/21) in the pre-existing renal insufficiency group. There were no statistical differences on the amounts of dye used and the frequencies of risk factors for contrast nephro-toxicity between the patients in pre-existing renal insufficiency group who developed nephrotoxicity and who did not. The renal function of all patients returned to the baseline value without dialysis or renal replacement therapy.CONCLUSION:
Pre-existing renal insufficiency is the most important risk factor for contrast nephrotoxicity. We need to take precautions and to have a proper protocol for the prevention of contrast nephrotoxicity in emergency care.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tomografia Computadorizada por Raios X
/
Prontuários Médicos
/
Incidência
/
Fatores de Risco
/
Terapia de Substituição Renal
/
Meios de Contraste
/
Creatinina
/
Diálise
/
Emergências
/
Serviços Médicos de Emergência
Tipo de estudo:
Estudo de etiologia
/
Guia de Prática Clínica
/
Estudo de incidência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Society of Emergency Medicine
Ano de publicação:
2003
Tipo de documento:
Artigo
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