A Case of Erdheim-Chester Disease with Laryngeal Involvement / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery
; : 738-741, 2016.
Article
em Ko
| WPRIM
| ID: wpr-643486
Biblioteca responsável:
WPRO
ABSTRACT
Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis with multi-organ involvement. Bones, cardiovascular system, central nervous system, kidney, skin and many different organs can be involved but laryngeal involvement has not been reported in literatures. The diagnosis of ECD was based on clinical manifestations and immunohistochemical findings including CD68(+), CD1a(-) and S100(-). Currently, Interferon-a is the most extensively studied agent in the treatment of ECD and serves as the 1st line of treatment. Surgical resection of involved lesions can be tried but it leads to temporary improvement. A 60-year-old man visited with respiratory symptoms because of ECD with laryngeal involvement. We resected the obstructive lesion to relieve the symptoms. Tissue biopsy gave a diagnosis of ECD. As it is rare to encounter ECD involving the larynx, we report this case with a review of literatures.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Pele
/
Biópsia
/
Sistema Cardiovascular
/
Histiocitose
/
Sistema Nervoso Central
/
Doença de Erdheim-Chester
/
Diagnóstico
/
Epiglote
/
Rim
/
Laringe
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Otolaryngology - Head and Neck Surgery
Ano de publicação:
2016
Tipo de documento:
Article