A Case of the Orbital Aspergillosis

ABSTRACT

Aspergillus is also a saprophytic, ubiquitous fungus that is normally not pathogenic in humans. When it does appear as a source of infection, the rhinoorbital route of entry seemes to parallel that of the Phacomycetes. We experienced a case of orbital aspergillosis in healthy woman. There was no intracraneal extension. In spite of local infiltration of amphotericin B solution through maxillary sinus and aggressive systemic amphotericin B therapy, ocular symptom and sign was not improved. So we performed orbital exenteration and adjunctive amphotericin B and itraconazol systemically. Six months later the patient is alive without recurrence. We reviewed the available literatures regarding this uncommon disease.