Three Cases of Extramedullary Plasmacytoma of the Head and Neck / 대한이비인후과학회지

ABSTRACT

The diagnosis and management of extramedullary plasmacytoma require the same range of clinical and laboratory expertise as for multiple myeloma. The primary treatment is radiotherapy, but surgery may also be required. We report three cases of extramedullary plasmacytoma located in the nasopharynx, neck, and nasal cavity respectively. The case of nasopharyngeal plasmacytoma, developed in a 55-year-old man, was associated with multiple bilateral cervical lymphadenopathy. Diagnosis was made with MRI, endoscopic nasopharyngeal biopsy, and bone marrow aspiration biopsy. Radiotherapy of 45 Gy resulted in the partial remission of primary and cervical lesions. The second case presented with cervical and retropharyngeal masses. Radiotherapy had not been successful, so the tumors were surgically excised. The third case was developed in the nose of a 43-year-old man complaining of nasal obstruction and epistaxis. Nasal cavity mass was identified as an extramedullary plasmacytoma. The patient underwent radiotherapy with 50 Gy with complete remission.